The biological clock is a well-known concept that indicates the regularity of the human body’s operation during the day. But what many people don’t know is that the skin, as the largest organ of the human body, also has a regularity.
During the day, the human body faces multiple threats from the environment, such as sunlight, stress, and haze. During this time, the skin will improve its protective function to resist these threats.
In the evening and at night, the skin will regenerate. Since the skin’s responsiveness and permeability seem to be better at night, these effects can be used to optimize the delivery and efficacy of cosmetic and medical active substances.
The skin works 24 hours a day, so skin care should also be done 24 hours a day. However, the environment is different during the day and night, and the state of the person is also different, so some distinctions can be made in the focus of skin care.
Daytime skin care: sun protection, moisturizing and antioxidants
The focus of daytime skin care should be to help the skin enhance its defense function. Cleansing, moisturizing and sun protection are essential, and anti-oxidation is also very important. Once the skin is in an excessively oxidative environment for a long time, many problems will arise, such as photoaging caused by ultraviolet rays, which is closely related to oxidative stress. Then there will be problems such as spots, dullness, fine lines, looseness, sagging and even collapse.
The factor that most affects the level of free radicals is ultraviolet rays. In addition, stress, poor sleep, bad mood, etc. will also release more free radicals and accelerate skin aging by affecting the mitochondria inside the cells. Therefore, during the day, we can use antioxidant products on the basis of regular skin care, and at the same time keep a happy mood.
Nighttime skin care focus: moisturizing and anti-oxidation
Data show that the skin temperature is higher at night, and the blood circulation volume per unit time is greater. It can be seen that when we sleep, the skin is not lazy, but busy repairing various accumulated damages.
If we do not sleep well, it will cause an increase in the number of free radicals in the human body, increasing the pressure of self-repair. Once there are too many oxygen free radicals in the dermis, it may stimulate a series of reactions in multiple enzymes, leading to consequences such as skin wrinkling. It may also slow down the microcirculation of subcutaneous blood, hinder the supply of cellular nutrients to the skin, reduce the water retention function of the skin, become dry, and increase wrinkles.
People who have anti-aging needs can focus on anti-oxidation as the focus of nighttime skin care. After all, the skin is always producing free radicals. Skin that is on duty 24 hours a day also needs comprehensive anti-oxidation care during the day + night.

